PIM1 Polyclonal Antibody

• Background :

  The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.

• Description :

  This is a PIM1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  Oncogene PIM 1, Oncogene PIM1, PIM 1, pim 1 kinase 44 kDa isoform, Pim 1 kinase, pim 1 oncogene (proviral integration site 1), Pim 1 oncogene, PIM, PIM1, pim1 kinase 44 kDa isoform, PIM1, Pim2, PIM3, Proto oncogene serine/threonine protein kinase Pim 1, Proto-oncogene

• Swiss Prot :

  P11309

• Accession Number :

  BC020224

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant protein of human PIM1

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC, ELISA

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.3 mg/mL

• Dilution :

  IHC 1:50-1:200

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG