USP2 Polyclonal Antibody

• Background:

  This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

• Description:

  This is a USP2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  41 kDa ubiquitin specific protease,41 kDa ubiquitin-specific protease, Deubiquitinating enzyme 2, Ubiquitin carboxyl terminal hydrolase 2, Ubiquitin carboxyl-terminal hydrolase 2, ubiquitin specific peptidase 2, Ubiquitin specific processing protease 2, Ubiquit

• Swiss Prot:

  O75604

• Accession Number:

  BC002854

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein of human USP2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.3 mg/mL

• Dilution:

  IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG