USP2 Polyclonal Antibody

CAT: 0866-RD75524A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD75524A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Description
This is a USP2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
41 kDa ubiquitin specific protease,41 kDa ubiquitin-specific protease, Deubiquitinating enzyme 2, Ubiquitin carboxyl terminal hydrolase 2, Ubiquitin carboxyl-terminal hydrolase 2, ubiquitin specific peptidase 2, Ubiquitin specific processing protease 2, Ubiquit
Swiss Prot
O75604
Accession Number
BC002854
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human USP2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.3 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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