CDKN2AIP Polyclonal Antibody

CAT: 0866-RD75301A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD75301A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CDKN2AIP (CDKN2A-interacting protein), also known as CARF, is a 580 amino acid protein that activates p53 via p14 ARF (alternate reading frame) -dependent and independent pathways. CDKN2AIP-dependent activation of p53, a protein that up-regulates growth arrest and apoptosis-related genes in response to stress signals, leads to an enhancement of p53 function. Expression levels of CDKN2AIP and p53 show an inverse relationship that is caused by a negative-feedback control via a proteasome-mediated degradation pathway. CDKN2AIP is expressed ubiquitously across tissue samples and, along with p14 ARF, is localized to the perinucleolar region within the nucleus.
Description
This is a CDKN2AIP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Calcium response factor, CARF, CARF, CDKN2A interacting protein, CDKN2A-interacting protein, Cdkn2aip, collaborates/cooperates with ARF (alternate reading frame) protein, Collaborator of ARF, FLJ20036
Swiss Prot
Q9NXV6
Accession Number
BC022270
Reactivity
Human
Immunogen
Recombinant protein of human CDKN2AIP
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.3 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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