MMP14 Polyclonal Antibody

• Background:

  Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

• Description:

  This is a MMP14 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Matrix metallopeptidase 14 (membrane inserted), Matrix metalloproteinase 14, Matrix metalloproteinase-14, Membrane type 1 matrix metalloproteinase, Membrane type 1 metalloprotease, Membrane type matrix metalloproteinase 1, Membrane-type matrix metalloproteinase

• Swiss Prot:

  P50281

• Accession Number:

  BC064803

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein of human MMP14

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.4 mg/mL

• Dilution:

  IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG