COPS5 Polyclonal Antibody

• Background:

  The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors

• Description:

  This is a COPS5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  38 kDa Mov34 homolog, COP9 (constitutive photomorphogenic) homolog subunit 5, COP9 constitutive photomorphogenic homolog subunit 5, COP9 signalosome complex subunit 5, COP9 signalosome subunit 5, Cop9 subunit 5, COPS 5, cops5, CSN 5, CSN5, CSN5, JAB 1, Jun activation

• Swiss Prot:

  Q92905

• Accession Number:

  BC001187

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant protein of human COPS5

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.9 mg/mL

• Dilution:

  WB 1:1000-1:5000, IHC 1:150-1:500

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  38 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG