DOK1 Polyclonal Antibody

• Background :

  The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

• Description :

  This is a DOK1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  Docking protein 1 62kD, Docking protein 1, DOK 1, DOK1, DOK1, Downstream of tyrosine kinase 1, p62 (dok), P62DOK, pp62

• Swiss Prot :

  Q99704

• Accession Number :

  BC114440

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant protein of human DOK1

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, ELISA

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.5 mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  52 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG