ABL1 Polyclonal Antibody

CAT: 0866-RD75053A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD75053A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t (9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.
Description
This is a ABL1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine protein kinase 1, Abl 1, ABL, ABL proto oncogene 1 non receptor tyrosine kinase, ABL1, ABL1, bcr/abl, bcr/c abl oncogene protein, c ABL, c abl oncogene 1 non receptor tyrosine kinase, c abl oncogene
Swiss Prot
P00519
Accession Number
BC117451
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human ABL1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.5 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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