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HDAC2 Polyclonal Antibody

CAT: 0866-RD71261A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD71261A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity.
Description
This is a HDAC2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
D10Wsu179e, HD 2, HD2, HDAC 2, Hdac2, HDAC2, Histone deacetylase 2 (HD2), Histone deacetylase 2, OTTHUMP00000017046, OTTHUMP00000227077, OTTHUMP00000227078, RPD3, transcriptional regulator homolog RPD3, YAF1, YY1 associated factor 1, YY1 transcription factor binding pro
Swiss Prot
Q92769
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Synthesized peptide derived from human HDAC2 around the non-phosphorylation site of Ser394.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC-p, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
55 kDa
Observed Molecular Weight
55 kDa
Host or Source
Rabbit
Isotype
IgG

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