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CASP9 Polyclonal Antibody

CAT: 0866-RD70881A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD70881A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) .Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Description
This is a CASP9 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
APAF-3, APAF3, Apoptosis related cysteine peptidase, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP-9, CASP9, CASP9, Caspase 9 apoptosis related cysteine peptidase, Caspase 9 Dominant Negative, Caspase 9c, Caspase-9, Caspase-9 subunit p10, ICE
Swiss Prot
P55211
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human Caspase-9 around the non-phosphorylation site of Thr125.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC-p, IF, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
46 kDa
Observed Molecular Weight
46 kDa
Host or Source
Rabbit
Isotype
IgG

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