CASP9 Polyclonal Antibody

• Background:

  Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) .Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

• Description:

  This is a CASP9 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  APAF-3, APAF3, Apoptosis related cysteine peptidase, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP-9, CASP9, CASP9, Caspase 9 apoptosis related cysteine peptidase, Caspase 9 Dominant Negative, Caspase 9c, Caspase-9, Caspase-9 subunit p10, ICE

• Swiss Prot:

  P55211

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthesized peptide derived from human Caspase-9 around the non-phosphorylation site of Thr125.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC-p, IF, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000

• Buffer:

  PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  46 kDa

• Observed Molecular Weight:

  46 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG