PYCARD Polyclonal Antibody

• Background :

  Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.

• Description :

  This is a PYCARD Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  Apoptosis associated speck like protein containing a CARD, Apoptosis-associated speck-like protein containing a CARD, ASC, ASC, CARD 5, CARD5, Caspase recruitment domain containing protein 5, Caspase recruitment domain protein 5, Caspase recruitment domain-contai

• Swiss Prot :

  Q9ULZ3

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthesized peptide derived from the N-terminal region of human ASC

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IHC-p, IF, ELISA

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000

• Buffer :

  PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  22 kDa

• Observed Molecular Weight :

  21 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG