ALPL Polyclonal Antibody

CAT: 0866-RD70571A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD70571A-01Size:60 μL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific) . The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described.
Description
This is a ALPL Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
AKP2, Alkaline phosphatase liver/bone/kidney, Alkaline phosphatase liver/bone/kidney isozyme, Alkaline phosphatase tissue nonspecific isozyme, Alkaline phosphatase, tissue-nonspecific isozyme, Alkaline phosphomonoesterase, Alpl, AP TNAP, AP-TNAP, APTNAP, BAP, FLJ4009
Swiss Prot
P05186, P09242, P08289
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein corresponding to Mouse Alkaline Phosphatase
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
200 μg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
57 kDa
Observed Molecular Weight
55 kDa
Host or Source
Rabbit
Isotype
IgG

Related Products

CatalogName
RD83678A-01ALPI Polyclonal Antibody
RD83753A-01ALPP Polyclonal Antibody
RDR-ALPL-Ra-48TestsRat Alkaline Phosphatase, Liver/Bone/Kidney (ALPL) ELISA Kit
RD-ALPL-Hu-01Human Alkaline Phosphatase, Liver/Bone/Kidney (ALPL) ELISA Kit
RDR-ALPL-Mu-01Mouse Alkaline Phosphatase, Liver/Bone/Kidney (ALPL) ELISA Kit
RDR-ALPL-Mu-96TestsMouse Alkaline Phosphatase, Liver/Bone/Kidney (ALPL) ELISA Kit
RDR-ALPL-Ra-96TestsRat Alkaline Phosphatase, Liver/Bone/Kidney (ALPL) ELISA Kit
RDR-ALPL-Mu-48TestsMouse Alkaline Phosphatase, Liver/Bone/Kidney (ALPL) ELISA Kit
RD-ALPL-Mu-48TestsMouse Alkaline Phosphatase, Liver/Bone/Kidney (ALPL) ELISA Kit
RDR-ALPL-Hu-48TestsHuman Alkaline Phosphatase, Liver/Bone/Kidney (ALPL) ELISA Kit

Alternative Products

CatalogName
E-AB-65787-01ALPL Polyclonal Antibody
E53P06612ALPL Rabbit Polyclonal Antibody
E55A05353Rat ALPL Polyclonal Antibody
PHC15301Anti-ALPL Polyclonal Antibody

Popular Products