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PPARA Polyclonal Antibody

CAT: 0866-RD70454A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD70454A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Peroxisome proliferator-activated receptor alpha (PPARA) is a ligand-activated transcription factor that belongs to the PPAR nuclear receptor superfamily. PPARA is essential in the modulation of lipid transport and metabolism, mainly through activating mitochondrial and peroxisomal fatty acid β-oxidation pathways. In addition, PPARA seems to decrease inflammation mainly through direct interaction with NF-κB, causing inhibition of its signaling pathway or reducing the activated levels of NF-κB and subsequent inflammation. Furthermore, PPARA was implicated in the attenuation of oxidative stress in alcoholic liver disease when treated with polyenephosphatidylcholine through downregulation of ROS-generating enzymes such as ethanol-inducible cytochrome P450 2E1 (CYP2E1), acyl-CoA oxidase, and NADPH oxidase.
Description
This is a PPARA Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
HPPAR, MGC2237, MGC2452, NR1C1, Nuclear receptor subfamily 1 group C member 1, OTTHUMP00000197740, OTTHUMP00000197741, Peroxisome proliferative activated receptor alpha, Peroxisome proliferator activated receptor alpha, Peroxisome proliferator-activated receptor a
Swiss Prot
P23204, P37230
Reactivity
Mouse, Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse PPARα
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.6 mg/mL
Dilution
IHC 1:200-1:500
Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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