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COL18A1 Polyclonal Antibody

CAT: 0866-RD70399A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD70399A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Description
This is a COL18A1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Antiangiogenic agent, COIA1, Col18a1, Collagen alpha 1 (XVIII) chain, Collagen type XVIII alpha 1, Endostatin, KNO, KNO1, KS, Multi functional protein MFP
Swiss Prot
P39060, P39061
Reactivity
Human, Mouse
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Endostatin
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1.1 mg/mL
Dilution
IHC 1:300-1:1000
Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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