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PDGFB Polyclonal Antibody

CAT: 0866-RD70329A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD70329A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Description
This is a PDGFB Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Becaplermin, PDGF 2, PDGF B chain, PDGF subunit B, PDGF-2, PDGF2, Pdgfb, PDGFB, Platelet derived growth factor 2, Platelet-derived growth factor B chain, Platelet-derived growth factor beta polypeptide, Platelet-derived growth factor subunit B, Proto-oncogene c-Sis, S
Reactivity
Mouse, Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse PDGFB
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
410 μg/mL
Dilution
WB 1:500-1:2000, IHC 1:200-1:400
Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
27 kDa
Observed Molecular Weight
27 kDa
Host or Source
Rabbit
Isotype
IgG

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