SMARCA4 Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

• Description:

  This is a SMARCA4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ATP dependent helicase SMARCA4, ATP-dependent helicase SMARCA4, BAF 190, BAF190, BAF190A, Brahma protein like 1, BRG1, BRG1 associated factor 190A, BRG1 protein, BRG1-associated factor 190A, BRM/SWI2 related gene 1, Global transcription activator homologous sequence

• Swiss Prot:

  P51532, Q3TKT4, Q8K1P7

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  KLH conjugated Synthetic peptide corresponding to Mouse BRG1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  410 μg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:200-1:600

• Buffer:

  PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  185 kDa

• Observed Molecular Weight:

  185 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG