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SMARCA4 Polyclonal Antibody

CAT: 0866-RD70326A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD70326A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Description
This is a SMARCA4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ATP dependent helicase SMARCA4, ATP-dependent helicase SMARCA4, BAF 190, BAF190, BAF190A, Brahma protein like 1, BRG1, BRG1 associated factor 190A, BRG1 protein, BRG1-associated factor 190A, BRM/SWI2 related gene 1, Global transcription activator homologous sequence
Swiss Prot
P51532, Q3TKT4, Q8K1P7
Reactivity
Human, Mouse, Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse BRG1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
410 μg/mL
Dilution
WB 1:500-1:2000, IHC 1:200-1:600
Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
185 kDa
Observed Molecular Weight
185 kDa
Host or Source
Rabbit
Isotype
IgG

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