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BECN1 Polyclonal Antibody

CAT: 0866-RD70303A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD70303A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.
Description
This is a BECN1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
APG6, ATG 6, ATG6, ATG6 autophagy related 6 homolog, Bcl-2-interacting protein beclin, Beclin 1 (coiled coil moesin like BCL2 interacting protein), Beclin 1 autophagy related, Beclin-1, Beclin1, BECN 1, Becn1, BECN1, Coiled coil myosin like BCL2 interacting protein, C
Swiss Prot
Q14457, O88597, Q91XJ1
Reactivity
Human, Mouse
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Beclin1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
2.6 mg/mL
Dilution
IHC 1:300-1:1000, IF 1:100-1:500
Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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