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Vimentin Polyclonal Antibody

CAT: 0866-RD70291A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD70291A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Vimentin, also named as VIM, belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha (TNFA; 191160) and inhibited by the antiinflammatory cytokine IL10 (124092), suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein,55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level.
Description
This is a Vimentin Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CTRCT30, Epididymis luminal protein 113, FLJ36605, HEL113, VIM, VIME, Vimentin
Swiss Prot
P08670, P20152, P31000
Reactivity
Human, Mouse, Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse vimentin
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1.1 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:200-1:800
Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
57 kDa
Observed Molecular Weight
57 kDa
Host or Source
Rabbit
Isotype
IgG

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