CYCS Polyclonal Antibody

• Background :

  Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.

• Description :

  This is a CYCS Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  Cytochrome C, Somatic, CYC, Cytochrome C, THC4, HCS.

• Swiss Prot :

  P99999, P62898, P62897

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  KLH conjugated Synthetic peptide corresponding to Mouse Cytochrome c

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IHC, IF

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1.5 mg/mL

• Dilution :

  WB 1:500-1:2000, IHC 1:500-1:1000, IF 1:200-1:800

• Buffer :

  PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  12 kDa

• Observed Molecular Weight :

  12 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG