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BBC3 Polyclonal Antibody

CAT: 0866-RD70215A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD70215A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.
Description
This is a BBC3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
BBC 3, Bbc3, BBC3, BCL 2 binding component 3, Bcl-2-binding component 3, BCL2 binding component 3, JFY 1, JFY-1, JFY1, p53 up regulated modulator of apoptosis, p53 up-regulated modulator of apoptosis, p53 Upregulated Modulator of Apoptosis, PUMA alpha, PUMA/JFY1
Swiss Prot
Q9BXH1
Reactivity
Human
Immunogen
Recombinant Human Bcl-2-binding component 3 protein
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
2 mg/mL
Dilution
IHC 1:100-1:200
Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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