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Lamin B1 Polyclonal Antibody

CAT: 0866-RD70141A-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0866-RD70141A-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD) .
Description
This is a Lamin B1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ADLD, lamin B1, Lamin-B1, LMN, LMN2, LMNB, Lmnb1, LMNB1, MGC111419, OTTHUMP00000159218
Swiss Prot
P70615
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Rat Lamin-B1 protein
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Antigen Affinity Purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:1000-1:2000 IHC 1:100-1:200
Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
67 kDa
Observed Molecular Weight
72 kDa
Host or Source
Rabbit
Isotype
IgG

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