MGMT Polyclonal Antibody

• Background :

  Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O (6) -alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma.

• Description :

  This is a MGMT Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  6 O methylguanine DNA methyltransferase,6-O-methylguanine-DNA methyltransferase, Agat, AGT, AI267024, EC 2.1.1.63, Methylated DNA protein cysteine methyltransferase, Methylated-DNA--protein-cysteine methyltransferase, Methylguanine DNA methyltransferase, MGC10702

• Swiss Prot :

  P16455

• Reactivity :

  Human

• Immunogen :

  Recombinant human Methylated DNA protein cysteine methyltransferase protein

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  2 mg/mL

• Dilution :

  WB 1:500-1:1000

• Buffer :

  PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  22 kDa

• Observed Molecular Weight :

  22 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG