APC Anti-Mouse CD51 Antibody

• Background:

  CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM) . The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.

• Description:

  This is a APC Anti-Mouse CD51 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Integrin alpha-V, αV integrin, Vitronectin Receptor, Integrin αV chain, ITGAV

• Gene ID:

  16410

• Swiss Prot:

  P43406

• Reactivity:

  Mouse

• Clonality:

  Monoclonal

• Conjugation:

  APC

• Type:

  Flow Cytometry Antibody

• Applications:

  FC

• Assay Type:

  Antibody

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.05% Proclin300, 1% BSA

• Storage Conditions:

  Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

• Host or Source:

  Rat

• Isotype:

  Rat IgG1, κ