RSPO1 Polyclonal Antibody

• Background:

  This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants.

• Description:

  This is a RSPO1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  RSPO1, CRISTIN3, RSPO

• Gene ID:

  284654

• Swiss Prot:

  Q2MKA7

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human RSPO1 (NP_001033722.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  IHC 1:50-1:100

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG