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NLRP2 Polyclonal Antibody

CAT: 0866-RD267966A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD267966A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR) . Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms.
Description
This is a NLRP2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
NLRP2, CLR19.9, NALP2, NBS1, PAN1, PYPAF2
Gene ID
55655
Swiss Prot
Q9NX02
Reactivity
Human
Immunogen
Recombinant fusion protein of human NLRP2 (NP_060322.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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