BAP1 Polyclonal Antibody

• Background:

  This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma.

• Description:

  This is a BAP1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  BAP1, HUCEP-13, UCHL2, hucep-6

• Gene ID:

  8314

• Swiss Prot:

  Q92560

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human BAP1 (NP_004647.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  80 kDa

• Observed Molecular Weight:

  80 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG