COMP Polyclonal Antibody

• Background:

  The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED) .

• Description:

  This is a COMP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  COMP, EDM1, EPD1, MED, PSACH, THBS5, TSP5

• Gene ID:

  1311

• Swiss Prot:

  P49747

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human COMP (NP_000086.2) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000 IF 1:10-1:100

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  77 kDa/82 kDa

• Observed Molecular Weight:

  110 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG