DOCK2 Polyclonal Antibody

• Background:

  The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP.

• Description:

  This is a DOCK2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  DOCK2, IMD40

• Gene ID:

  1794

• Swiss Prot:

  Q92608

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human DOCK2 (NP_004937.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  38 kDa/211 kDa

• Observed Molecular Weight:

  240 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG