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INS Polyclonal Antibody

CAT: 0866-RD267409A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD267409A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
Description
This is a INS Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10, INS, Insulin, insulin
Gene ID
3630
Swiss Prot
P01308
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human INS (NP_000198.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:200 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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