Amphiregulin Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha) . The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions.

• Description:

  This is a Amphiregulin Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  AREG, AR, AREGB, CRDGF, SDGF, amphiregulin

• Gene ID:

  374

• Swiss Prot:

  P15514

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human Amphiregulin (NP_001648.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  27 kDa

• Observed Molecular Weight:

  35 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG