IL10RA Polyclonal Antibody

CAT: 0866-RD267338A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD267338A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
Description
This is a IL10RA Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
IL10RA, CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R
Gene ID
3587
Swiss Prot
Q13651
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human IL10RA (NP_001549.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:200 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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