EIF2AK3 Polyclonal Antibody

• Background:

  The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.

• Description:

  This is a EIF2AK3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  EIF2AK3, PEK, PERK, WRS

• Gene ID:

  9451

• Swiss Prot:

  Q9NZJ5

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein of human EIF2AK3

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  125 kDa

• Observed Molecular Weight:

  160 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG