SIRT1 Polyclonal Antibody

• Background:

  This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

• Description:

  This is a SIRT1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  SIR2, SIR2L1, SIR2alpha, SIRT1, sirtuin 1

• Gene ID:

  23411

• Swiss Prot:

  Q96EB6

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human SIRT1

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG