Products for Research Use Only

TLR5 Polyclonal Antibody

CAT: 0866-RD267080A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD267080A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.
Description
This is a TLR5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
MELIOS, SLE1, SLEB1, TIL3, TLR5
Gene ID
7100
Swiss Prot
O60602
Reactivity
Human
Immunogen
Recombinant fusion protein of human TLR5 (NP_003259.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
97 kDa
Observed Molecular Weight
100 kDa
Host or Source
Rabbit
Isotype
IgG