BBC3 Polyclonal Antibody

• Background:

  This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.

• Description:

  This is a BBC3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  BBC3, JFY-1, JFY1, PUMA

• Gene ID:

  27113

• Swiss Prot:

  Q96PG8, Q9BXH1

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human BBC3 (NP_001120713.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000 IF 1:50-1:100

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  10 kDa/14 kDa/20 kDa/26 kDa

• Observed Molecular Weight:

  20 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG