DMTF1 Polyclonal Antibody

• Background:

  This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

• Description:

  This is a DMTF1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  DMTF1, DMP1, DMTF, MRUL, hDMP1

• Gene ID:

  9988

• Swiss Prot:

  Q9Y222

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein of human DMTF1 (NP_066968.3) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  84 kDa

• Observed Molecular Weight:

  85 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG