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CDK6 Polyclonal Antibody

CAT: 0866-RD266778A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD266778A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Description
This is a CDK6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CDK6, MCPH12, PLSTIRE
Gene ID
1021
Swiss Prot
Q00534
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human CDK6 (NP_001250.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:200 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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