PEX12 Polyclonal Antibody

• Background :

  This gene belongs to the peroxin-12 family. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS) .

• Description :

  This is a PEX12 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  PEX12, PAF-3, PBD3A

• Gene ID :

  5193

• Swiss Prot :

  O00623

• Reactivity :

  Human

• Immunogen :

  Recombinant fusion protein of human PEX12 (NP_000277.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  40 kDa

• Observed Molecular Weight :

  41 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG