PEX12 Polyclonal Antibody

• Background:

  This gene belongs to the peroxin-12 family. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS) .

• Description:

  This is a PEX12 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  PEX12, PAF-3, PBD3A

• Gene ID:

  5193

• Swiss Prot:

  O00623

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein of human PEX12 (NP_000277.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  40 kDa

• Observed Molecular Weight:

  41 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG