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AGT Polyclonal Antibody

CAT: 0866-RD266513A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD266513A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Description
This is a AGT Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
AGT, ANHU, hFLT1
Gene ID
183
Swiss Prot
P01019
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human AGT (NP_000020.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
53 kDa
Observed Molecular Weight
53 kDa
Host or Source
Rabbit
Isotype
IgG

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