ACACA Polyclonal Antibody

• Background:

  Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.

• Description:

  This is a ACACA Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ACACA, ACAC, ACACAD, ACC, ACC1, ACCA

• Gene ID:

  31

• Swiss Prot:

  Q13085

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human ACACA

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000 IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  257 kDa/259 kDa/265 kDa/269 kDa

• Observed Molecular Weight:

  240 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG