CAV1 Polyclonal Antibody

CAT: 0866-RD266490A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD266490A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
Description
This is a CAV1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
BSCL3, CGL3, LCCNS, MSTP085, PPH3, VIP21, CAV1
Gene ID
857
Swiss Prot
Q03135
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human CAV1 (NP_001744.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
17 kDa/20 kDa
Observed Molecular Weight
20 kDa/23 kDa
Host or Source
Rabbit
Isotype
IgG

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