PFKFB3 Polyclonal Antibody

• Background :

  The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Description :

  This is a PFKFB3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  PFKFB3, IPFK2, PFK2, iPFK-2

• Gene ID :

  5209

• Swiss Prot :

  Q16875

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein of human PFKFB3 (NP_004557.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IF

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  IF 1:50-1:200

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG