ABCB11 Polyclonal Antibody

• Background:

  The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.

• Description:

  This is a ABCB11 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP

• Gene ID:

  8647

• Swiss Prot:

  O95342

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human ABCB11 (NP_003733.2) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG