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TPSAB1 Polyclonal Antibody

CAT: 0866-RD266289A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD266289A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
Description
This is a TPSAB1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
TPSAB1, TPS1, TPS2, TPSB1
Gene ID
7177
Swiss Prot
Q15661
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human TPSAB1 (NP_003285.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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