MRPL2 Polyclonal Antibody

• Background:

  Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

• Description:

  This is a MRPL2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  MRPL2, CGI-22, MRP-L14, RPML14

• Gene ID:

  51069

• Swiss Prot:

  Q5T653

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human MRPL2 (NP_057034.2) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  33 kDa

• Observed Molecular Weight:

  33 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG