MKL1 Polyclonal Antibody

• Background:

  The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.

• Description:

  This is a MKL1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  MKL1, BSAC, MAL, MRTF-A

• Gene ID:

  57591

• Swiss Prot:

  Q969V6

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human MKL1 (NP_065882.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000 IF 1:50-1:100

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  98 kDa

• Observed Molecular Weight:

  150 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG