Kaolin

• Description:

  Kaolin is a family of kaolinitic clays, which is found in the earth's crust. Kaolin alleviates the toxicity of graphene oxide for mammalian cells. Kaolin can be utilized in industrial, cosmetic and medical fields, excipient[1][2][3][4][5].

• UNSPSC:

  12352300

• Hazard Statement:

  H302, H315, H319, H332, H335, H372

• Target:

  Biochemical Assay Reagents; Interleukin Related; Reactive Oxygen Species (ROS) ; TNF Receptor

• Type:

  Reference compound

• Related Pathways:

  Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/kaolin.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [Kaolin]

• Molecular Formula:

  Al2Si2O5 (OH) 4

• Molecular Weight:

  258.16

• Precautions:

  H302, H315, H319, H332, H335, H372

• References & Citations:

  [1]Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.|[2]Zhang Z H, et al. Geopolymer from kaolin in China: An overview[J]. Applied Clay Science, 2016, 119: 31-41.|[3]Rozhina E, et al. Kaolin alleviates the toxicity of graphene oxide for mammalian cells. Medchemcomm. 2019 Jun 10;10 (8) :1457-1464.|[4]Kato T, et al. Effect of physicochemical character differences on the genotoxic potency of kaolin. Genes Environ. 2017 May 1;39:12. |[5]Sahu AP, Shanker R, Zaidi SH. Pulmonary response to kaolin, mica and talc in mice. Exp Pathol (Jena) . 1978;16 (1-6) :276-82.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1332-58-7]