Products for Research Use Only

ANO1 Polyclonal Antibody

CAT: 0866-RD265774A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD265774A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TMEM16A, also known as DOG1, ORAOV2, TAOS2 or ANO1 (anoctamin 1), is a 986 amino acid multi-pass membrane protein that localizes to both the cell membrane and the cytoplasm and belongs to the anoctamin family. Expressed in a variety of tissues with highest expression in skeletal muscle and liver, TMEM16A functions as a calcium-activated chloride channel that is required for normal tracheal development. Human TMEM16A shares 90% sequence identity with its mouse counterpart, suggesting a conserved role between species. TMEM16A is present in breast, pancreatic, gastric, and uterine cancers, as well as in neck, ovarian and parathyroid tumors, suggesting a role for TMEM16A in carcinogenesis. Three isoforms of TMEM16A exist due to alternative splicing events.
Description
This is a ANO1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ANO1, DOG1, ORAOV2, TAOS2, TMEM16A
Gene ID
55107
Swiss Prot
Q5XXA6
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human ANO1 (NP_060513.5) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IF 1:100-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG