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MEP1B Polyclonal Antibody

CAT: 0866-RD265731A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD265731A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.
Description
This is a MEP1B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
MEP1B
Gene ID
4225
Swiss Prot
Q16820
Reactivity
Mouse
Immunogen
Recombinant fusion protein of human MEP1B (NP_005916.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
79 kDa
Observed Molecular Weight
105 kDa
Host or Source
Rabbit
Isotype
IgG

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