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WISP2 Polyclonal Antibody

CAT: 0866-RD253562A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD253562A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.
Description
This is a WISP2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CCN family member 5, CCN5, Connective tissue growth factor like protein, Connective tissue growth factor related protein 58, Connective tissue growth factor-like protein, Connective tissue growth factor-related protein 58, CT58, CTGF L, CTGF-L, WISP 2, WISP-2, Wisp2
Swiss Prot
O76076
Accession Number
NP003872
Reactivity
Human
Immunogen
Synthetic peptide of human WISP2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.8 mg/mL
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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