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YBX1 Polyclonal Antibody

CAT: 0866-RD253542A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD253542A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This protein mediates pre-mRNA alternative splicing regulation. It binds to splice sites in pre-mRNA and regulates splice site selection and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It can regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro) .
Description
This is a YBX1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
BP 8, CBF-A, CCAAT binding transcription factor I subunit A, CCAAT-binding transcription factor I subunit A, CSDA2, CSDB, DBPB, DNA binding protein B, DNA-binding protein B, EFI-A, Enhancer factor I subunit A, MDR NF1, MGC104858, MGC110976, MGC117250, NSEP 1, NSEP1, Nucle
Swiss Prot
P67809
Accession Number
NP004550
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human YBX1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.6 mg/mL
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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